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For a seafood twist on a classic Italian favorite, look no further than Garlic Butter Shrimp Scampi Lasagna! This indulgent dish combines tender layers of lasagna noodles with succulent shrimp, rich garlic butter sauce, and a melty, cheesy topping. Perfect for dinner parties, date nights, or any time you crave a luxurious seafood meal.
Combining the flavors of shrimp scampi with the comforting layers of lasagna creates a crowd-pleasing dish that’s both elegant and hearty. With garlic, lemon, and fresh herbs highlighting the seafood, every bite bursts with flavor.

Why Garlic Butter Shrimp Scampi Lasagna Works
This recipe balances richness and freshness perfectly:
- Garlic butter sauce coats the shrimp and noodles without being overly heavy.
- Lemon juice brightens the flavor and cuts through the richness.
- Creamy ricotta and melty mozzarella add texture and indulgence.
- Fresh parsley adds color and herbaceous notes that elevate the dish.
Ingredients
Lasagna Layers
- 9–12 lasagna noodles (cooked al dente)
- 1 lb large shrimp, peeled and deveined
- 4 tbsp unsalted butter
- 4 cloves garlic, minced
- 1/2 cup white wine (or chicken broth)
- Juice of 1 lemon
- 1/2 tsp red pepper flakes (optional)
- 1 cup ricotta cheese
- 1 1/2 cups shredded mozzarella cheese
- 1/2 cup grated Parmesan cheese
- 1/4 cup fresh parsley, chopped
- Salt and pepper, to taste

Garlic Butter Sauce
- 6 tbsp butter
- 4 cloves garlic, minced
- 1/2 cup heavy cream
- 1/4 tsp salt
- 1/4 tsp black pepper
- Juice of 1/2 lemon
Instructions
- Preheat oven to 375°F (190°C). Grease a 9×13-inch baking dish.
- Cook lasagna noodles according to package directions. Drain and set aside.
- In a skillet, melt 4 tbsp butter over medium heat. Add minced garlic and sauté 1–2 minutes until fragrant.
- Add shrimp and cook 2–3 minutes per side until pink and opaque. Remove from skillet and set aside.
- Deglaze skillet with white wine or chicken broth and lemon juice. Simmer 2 minutes to reduce slightly.
- In a saucepan, melt 6 tbsp butter, add garlic, cream, lemon juice, salt, and pepper. Simmer 2–3 minutes until sauce slightly thickens.
- Spread a thin layer of garlic butter sauce on the bottom of the prepared baking dish.
- Layer 3–4 lasagna noodles, then half the shrimp, half the ricotta, a third of the mozzarella, a third of the Parmesan, and a layer of sauce. Repeat layers. Top with remaining noodles, sauce, and remaining cheese.
- Cover with foil and bake 20 minutes. Remove foil and bake an additional 10–15 minutes until cheese is golden and bubbly.
- Let lasagna rest 5–10 minutes before slicing. Garnish with fresh parsley. Serve warm.
Tips for the Perfect Shrimp Scampi Lasagna
- Do not overcook shrimp: Shrimp cooks quickly; remove from heat while slightly underdone since it will bake in the oven.
- Use fresh garlic: Garlic flavor is key in both the scampi and the sauce.
- Layer carefully: Ensure even distribution of shrimp, cheese, and sauce to balance every bite.
- Rest before slicing: This helps the lasagna hold its shape.
Variations
- Spicy Shrimp Scampi Lasagna: Add extra red pepper flakes for a kick.
- Cheesy Lovers: Mix in fontina or provolone with mozzarella for a gooier texture.
- Vegetable Twist: Add sautéed spinach, zucchini, or roasted red peppers between layers.
- White Wine-Free Version: Use chicken or vegetable broth in place of wine.

Serving Suggestions
- Pair with a crisp Caesar salad or arugula salad for freshness.
- Serve with garlic bread to soak up the delicious sauce.
- Complement with a chilled glass of Sauvignon Blanc or Pinot Grigio.
Make-Ahead & Storage
- Make-ahead: Assemble without baking and refrigerate up to 24 hours. Bake when ready.
- Storage: Refrigerate leftovers in an airtight container for up to 3 days.
- Freezing: Wrap tightly with foil and freeze for up to 2 months. Thaw overnight in refrigerator before baking.
Why This Recipe Works
Garlic Butter Shrimp Scampi Lasagna is a fusion of two favorites: the bright, buttery flavors of shrimp scampi with the hearty comfort of lasagna. Combining rich cream, sharp cheeses, and fresh herbs ensures a luxurious meal that’s easy to love.
Fun Fact
Shrimp scampi is a classic Italian-American dish traditionally served with pasta. Turning it into lasagna adds layers of flavor, indulgence, and a show-stopping presentation perfect for special occasions.
Final Thoughts
If you want a seafood lasagna that elevates dinner to restaurant-quality indulgence, Garlic Butter Shrimp Scampi Lasagna is your answer. Perfectly layered, bursting with flavor, and topped with golden, melty cheese, this dish will impress any seafood lover at the table.

Garlic Butter Shrimp Scampi Lasagna
Ingredients
Equipment
Method
- Preheat oven and grease baking dish.
- Cook lasagna noodles and set aside.
- Cook shrimp in butter and garlic, remove and set aside.
- Deglaze skillet with white wine and lemon juice.
- Prepare garlic butter sauce with butter, garlic, cream, lemon juice, salt, and pepper.
- Layer noodles, shrimp, ricotta, mozzarella, Parmesan, and sauce.
- Top with remaining noodles, sauce, and cheese.
- Cover with foil and bake 20 minutes, remove foil and bake 10–15 minutes more.
- Rest 5–10 minutes before slicing and garnish with parsley.



